Table 1

Chronic angiotensin II infusion (2000 ng/kg/min) induces hypertension via blood cell associated AT1aR.

Experimental group

Mean arterial pressure

(mmHg)

Wild type mice (WT) - saline loaded (- saline)

(n = 9)

110.8 ± 1.8

WT - angiotensin II loaded (- Ang II)

(n = 10)

125.4 ± 4.9*

AT1aR knockout mice (AT1aR^-/-) - Ang II

(n = 6)

103.4 ± 4.0^†

WT bone marrow chimera mice reconstructed with WT bone marrow (WT→WT) - saline

(n = 7)

96.6 ± 2.0

WT→WT - Ang II

(n = 8)

115.1 ± 6.1^‡

AT1aR^-/-→WT - Ang II

(n = 6)

108.9 ± 3.2^†

Data are presented as mean ± SE. * denotes P < 0.05 vs WT - saline, † denotes p < 0.05 relative to WT - Ang II, ‡ denotes P < 0.05 vs WT→WT - saline

Nagai et al. Experimental & Translational Stroke Medicine 2011 3:15   doi:10.1186/2040-7378-3-15