Figure 5.

EP2 receptor deletion increases neurologic deficit scores and infarct volume of mice subjected to pMCAO. Seven days after being subjected to pMCAO, mice were assessed for neurologic dysfunction and then sacrificed. (A) Representative images show TTC-stained infarcted brain slices from WT (left) and EP2^-/- (right) mice. (B) The bar graph shows the corrected cortical infarct volumes of WT and EP2^-/- mice. (C) Neurologic deficit scores at 7 days after ischemia were significantly higher in EP2^-/- mice (n = 7) than in WT mice (n = 8). **P < 0.008.